RCSB PDB

RCSB PDB is the home of the Protein Data Bank, the single worldwide repository for experimentally determined three-dimensional structures of biological macromolecules including proteins, nucleic acids, and complex assemblies. Operated by a consortium of institutions including Rutgers University and the University of California San Diego, it currently archives over 220,000 structures that have been determined by X-ray crystallography, cryo-electron microscopy, and NMR spectroscopy. For structural biologists, biochemists, drug designers, and students learning about molecular biology, RCSB PDB is an indispensable resource. You can search for structures by protein name, organism, sequence similarity, or ligand type, and then explore interactive 3D visualizations right in your web browser. Each structure entry includes detailed metadata about the experimental methods used, resolution, associated publications, and links to related sequence and functional databases. The platform has played a crucial role in enabling structure-based drug design, where researchers use atomic-level structural information to design molecules that can precisely target disease-related proteins.